Biological Activity
Water-soluble form of DNQX (Cat. No. 0189). Selective non-NMDA receptor antagonist.
Technical Data
| M. Wt | 296.1 |
| Formula | C8H2N4O6Na2 |
| Storage | Desiccate at RT |
| Purity | ≥98% (HPLC) |
| CAS Number | 1312992-24-7 |
| PubChem ID | 45073428 |
| InChI Key | GPSBSOYURFUVKJ-UHFFFAOYSA-L |
| Smiles | [Na+].[Na+].[O-]C1=C([O-])N=C2C=C(C(=CC2=N1)[N+]([O-])=O)[N+]([O-])=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 31.4 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 296.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.38 mL | 16.89 mL | 33.77 mL |
| 5 mM | 0.68 mL | 3.38 mL | 6.75 mL |
| 10 mM | 0.34 mL | 1.69 mL | 3.38 mL |
| 50 mM | 0.07 mL | 0.34 mL | 0.68 mL |
Molarity Calculator
Reconstitution Calculator
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Product Datasheets
References
References are publications that support the products' biological activity.
Honore et al (1988) Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists. Science 241 701 PMID: 2899909
Watkins et al (1990) Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists. TiPS 11 25 PMID: 2155495
Keywords: DNQX disodium salt, supplier, Water-soluble, salt, Glutamate, Kainate, Receptors, iGluR, Ionotropic, AMPA, non-NMDA, AMPA, Receptors, Kainate, Receptors, AMPA, Receptors, Tocris Bioscience
