Tocris/3-Deazaneplanocin A hydrochloride/4703/1/1 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/3-Deazaneplanocin A hydrochloride/4703/1/1 mg

Tocris/3-Deazaneplanocin A hydrochloride/4703/1/1 mg

商品编号： 4703/1

品牌： Tocris Bioscience

市场价： ¥3300.00

美元价： 1980.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:EZH2histonemethyltransferaseinhibitor

AlternativeNames:DZNep,NSC617989

ChemicalName:(1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diolhydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Histonemethyltransferaseinhibitor;decreasesglobalhistonemethylation.InhibitsEZH2histonemethyltransferaseands-adenosylhomocysteine(SAH)hydrolaseactivity.Blockstrimethylationoflysine27onhistoneH3andlysine20onhistoneH4invitro.Inducesapoptosisinmultiplecancercelllinesandhasnoapoptoticeffectonnormalcells.EnhancesOct4expressioninchemicallyinducedpluripotentstemcells(CiPSCs).

TechnicalData

M.Wt	298.73
Formula	C₁₂H₁₄N₄O₃.HCl
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	120964-45-6
PubChemID	14563109
InChIKey	UNSKMHKAFPRFTI-FDKLLANESA-N
Smiles	OCC([C@@H](O)[C@H]3O)=C[C@H]3N2C=NC1=C(N)N=CC=C12.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	water	2.99	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight298.73.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.35mL	16.74mL	33.48mL
5mM	0.67mL	3.35mL	6.7mL
10mM	0.33mL	1.67mL	3.35mL
50mM	0.07mL	0.33mL	0.67mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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