Biological Activity
Selective inhibitor of α-mannosidase I.
Technical Data
| M. Wt | 199.63 |
| Formula | C6H13NO4.HCl |
| Storage | Desiccate at RT |
| CAS Number | 73465-43-7 |
| PubChem ID | 11019872 |
| InChI Key | ZJIHMALTJRDNQI-MVNLRXSJSA-N |
| Smiles | Cl[H].OC[C@H]1NC[C@@H](O)[C@@H](O)[C@@H]1O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 9.98 | 50 |
Preparing Stock Solutions
The following data is based on the product molecular weight 199.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 5.01 mL | 25.05 mL | 50.09 mL |
| 5 mM | 1 mL | 5.01 mL | 10.02 mL |
| 10 mM | 0.5 mL | 2.5 mL | 5.01 mL |
| 50 mM | 0.1 mL | 0.5 mL | 1 mL |
Molarity Calculator
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Product Datasheets
References
References are publications that support the products' biological activity.
Bischoff et al (1986) The use of 1-deoxymannojirimycin to evaluate the role of various α-mannosidases in oligosaccharide processing in intact cells. J.Biol.Chem. 261 4766 PMID: 2937779
Bischoff and Kornfeld (1984) The effect of 1-deoxymannojirimycin on rat liver α-mannosidases. Biochem.Biophys.Res.Commun. 125 324 PMID: 6239623
Fuhrmann et al (1984) Novel mannosidase inhibitor blocking conversion of high mannose to complex oligosaccharides. Nature 307 755 PMID: 6230538
Keywords: 1-Deoxymannojirimycin hydrochloride, supplier, α-mannosidase, alpha-mannosidase, I, inhibitors, inhibits, a-Mannosidase, Glycosylases, Carbohydrate, Metabolism, antibiotics, Glycosylases, Antibiotics, Glycosylases, Tocris Bioscience
