Biological Activity
5-HT receptor antagonist; partial agonist at adrenergic and dopaminergic receptors.
Compound Libraries
Dihydroergocristine mesylate is also offered as part of the Tocriscreen Plus. Find out more about compound libraries available from Tocris.
Technical Data
| M. Wt | 707.84 |
| Formula | C35H41N5O5.CH3SO3H |
| Storage | Store at RT |
| Purity | ≥98% (HPLC) |
| CAS Number | 24730-10-7 |
| PubChem ID | 444034 |
| InChI Key | SPXACGZWWVIDGR-SPZWACKZSA-N |
| Smiles | CS(=O)(O)=O.[H][C@]4([C@@]([H])3C[C@@H]([C@@](N[C@@]5([C@H](C)C)C(N([C@@]([H])(CC8=CC=CC=C8)C(N7[C@]([H])6CCC7)=O)[C@@]6(O)O5)=O)=O)CN4C)CC1=CNC2=C1C3=CC=C2 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 17.7 | 25 |
Preparing Stock Solutions
The following data is based on the product molecular weight 707.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.41 mL | 7.06 mL | 14.13 mL |
| 5 mM | 0.28 mL | 1.41 mL | 2.83 mL |
| 10 mM | 0.14 mL | 0.71 mL | 1.41 mL |
| 50 mM | 0.03 mL | 0.14 mL | 0.28 mL |
Molarity Calculator
Reconstitution Calculator
Dilution Calculator
Product Datasheets
References
References are publications that support the products' biological activity.
Drago (1988) Dihydroergocristine and memory alterations of aged male rats. Pharmacol.Biochem.Behav. 30 961 PMID: 3147464
Keywords: Dihydroergocristine mesylate, supplier, Partial, α-adrenoceptors, α-adrenoceptor, alpha-adrenoceptors, agonists, Non-Selective, dopamine, receptors, partial, α-adrenergic, alpha-adrenergic, a-adrenergic, 5-HT, antagonists, dopaminergic, D2-like, 5-Hydroxytryptamine, Serotonin, 5-HT3, Non-selective, Adrenergic, Alpha, Receptors, Non-selective, Dopamine, Non-selective, 5-HT, 5-HT3, Receptors, Non-selective, Adrenergic, Alpha, Receptors, Tocris Bioscience
