Biological Activity
Protein kinase C inhibitor.
Technical Data
| M. Wt | 301.51 |
| Formula | C18H39NO2 |
| Storage | Desiccate at -20°C |
| CAS Number | 3102-56-5 |
| PubChem ID | 5746414 |
| InChI Key | OTKJDMGTUTTYMP-QZTJIDSGSA-N |
| Smiles | OC[C@](N)([H])[C@H](O)CCCCCCCCCCCCCCC |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 100 mM in DMSO |
Preparing Stock Solutions
The following data is based on the product molecular weight 301.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.32 mL | 16.58 mL | 33.17 mL |
| 5 mM | 0.66 mL | 3.32 mL | 6.63 mL |
| 10 mM | 0.33 mL | 1.66 mL | 3.32 mL |
| 50 mM | 0.07 mL | 0.33 mL | 0.66 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Yung et al (1993) Differential regulation of protein kinase C isoenzymes during sphinganine potentiation of retinoic acid-induced granulocytic differentiation in human leukemia HL-60 cells. Biochem.Biophys.Res.Commun. 196 1390 PMID: 8250895
Yung et al (1994) Sphinganine potentiation of dimethyl sulfoxide-induced granulocyte differentiation, increase of alkaline phosphatase activity and decrease of protein kinase C activity in a human leukemia cell line (HL-60). Biochem.Biophys.Res.Commun. 199 888 PMID: 8135836
Keywords: Dihydrosphingosine, supplier, Protein, kinase, C, inhibitors, inhibits, PKC, Kinases, Sphinganine, Protein, Kinase, C, Protein, Kinase, C, Tocris Bioscience
