Tocris/Dolasetron mesylate/5629/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/Dolasetron mesylate/5629/50/50 mg

Tocris/Dolasetron mesylate/5629/50/50 mg

商品编号： 5629/50

品牌： Tocris Bioscience

市场价： ¥6300.00

美元价： 3780.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Potentandselective5-HT₃antagoNIST

ChemicalName:3-Oxooctahydro-2,6-methano-2H-quinolizin-8-yl1H-indole-3-carboxylatemethanesulfonate

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselective5-HT₃receptorantagonist(pIC₅₀=7.55).Exhibits200-foldselectivityfor5-HT₃over5-HT_1A,5-HT_1Band5-HT₂receptors,andarangeofotherGPCRs.Blocksthe5-HT-elicitedvonBezold-Jarischreflexinratsandsuppressescisplatin-inducedvomitinginferrets.

CompoundLibraries

DolasetronmesylateisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	420.48
Formula	C₁₉H₂₀N₂O₃.CH₃SO₃H
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	115956-13-3
PubChemID	60653
InChIKey	PSGRLCOSIXJUAL-VPUTYDRXSA-N
Smiles	O=C(O[C@@H]3C[C@H](C5)N(CC(C5C4)=O)[C@@]4([H])C3)C2=CNC1=CC=CC=C12.CS(=O)(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	42.05	100
	water	42.05	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight420.48.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.38mL	11.89mL	23.78mL
5mM	0.48mL	2.38mL	4.76mL
10mM	0.24mL	1.19mL	2.38mL
50mM	0.05mL	0.24mL	0.48mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets