Biological Activity
Endogenous neurotransmitter that acts as an agonist at dopamine D1-5 receptors. Synthesized in the substantia nigra and ventral tegmental area, and is a precursor in noradrenalin and adrenalin biosynthesis. Caged dopamine is also available (Cat. No 3992).
Technical Data
| M. Wt | 189.64 |
| Formula | C8H11NO2.HCl |
| Storage | Store at -20°C |
| Purity | ≥99% (HPLC) |
| CAS Number | 62-31-7 |
| PubChem ID | 65340 |
| InChI Key | CTENFNNZBMHDDG-UHFFFAOYSA-N |
| Smiles | NCCC1=CC(O)=C(O)C=C1.Cl |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 18.96 | 100 | |
| water | 18.96 | 100 |
Preparing Stock Solutions
The following data is based on the product molecular weight 189.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 5.27 mL | 26.37 mL | 52.73 mL |
| 5 mM | 1.05 mL | 5.27 mL | 10.55 mL |
| 10 mM | 0.53 mL | 2.64 mL | 5.27 mL |
| 50 mM | 0.11 mL | 0.53 mL | 1.05 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Rivonello et al (2007) Novel insights into dopamine receptor pharmacology. Eur.J.Endocrinol. 156 S13 PMID: 17413183
Cools (2008) Role of dopamine in the motivational and cognitive control of behavior. Neuroscientist 14 381 PMID: 18660464
Fitzgerald and Dinan (2008) Prolactin and dopamine: what is the connection? A review article. J.Psychopharmacol. 22 S12 PMID:
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