Tocris/E-4031 dihydrochloride/1808/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/E-4031 dihydrochloride/1808/10/10 mg

Tocris/E-4031 dihydrochloride/1808/10/10 mg

商品编号： 1808/10

品牌： Tocris Bioscience

市场价： ¥3780.00

美元价： 2268.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:K_V11.1(hERG)channelblocker;inhibitsrapiddelayedrectifierK⁺current(I_Kr)

ChemicalName:N-[4-[[1-[2-(6-Methyl-2-pyridinyl)ethyl]-4-piperidinyl]carbonyl]phenyl]methanesulfonamidedihydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveblockerofK_V11.1(hERG)channels;inhibitstherapiddelayed-rectifierK⁺current(I_Kr).ReversIBLyprolongsactionpotentialdurationinguineapigpapillarymuscleandisolatedventricularmyocytes,withoutaffectingNa⁺orCa²⁺inwardcurrents.ClassIIIantiarrhythmicagent.

CompoundLibraries

E-4031dihydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	474.44
Formula	C₂₁H₂₇N₃O₃S.2HCl
Storage	DesiccateatRT
Purity	≥98%(HPLC)
CASNumber	113559-13-0
PubChemID	3087190
InChIKey	ZQBNWMFBOSOOLX-UHFFFAOYSA-N
Smiles	Cl.Cl.CC1=CC=CC(CCN2CCC(CC2)C(=O)C2=CC=C(NS(C)(=O)=O)C=C2)=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	23.72	50
	water	47.44	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight474.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.11mL	10.54mL	21.08mL
5mM	0.42mL	2.11mL	4.22mL
10mM	0.21mL	1.05mL	2.11mL
50mM	0.04mL	0.21mL	0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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TechnicalData

SolubilityData

PreparingStockSolutions

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