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当前位置: 首页 > 产品中心 > DNA_polymerase > Tocris/EB 47/4140/50/50毫克
商品详细Tocris/EB 47/4140/50/50毫克
Tocris/EB 47/4140/50/50毫克
Tocris/EB 47/4140/50/50毫克
商品编号: 4140/50
品牌: Tocris Bioscience
市场价: ¥19300.00
美元价: 11580.00
产地: 美国(厂家直采)
公司:
产品分类: DNA聚合酶
公司分类: DNA_polymerase
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:PotentPARP-1inhibitor
ChemicalName:5'-Deoxy-5'-[4-[2-[(2,3-Dihydro-1-oxo-1H-isoindol-4-yl)amino]-2-oxoethyl]-1-piperazinyl]-5'-oxoadenosinedihydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentinhibitorofPARP-1(IC50=45nM).Reducesinfarctvolumeinbotharattransientmiddlecerebralarterialocclusionmodelandacardiacreperfusionmodel.

CompoundLibraries

EB47isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt610.45
FormulaC24H27N9O6.2HCl
StorageStoreat-20°C
Purity≥99%(HPLC)
CASNumber1190332-25-2
PubChemID90488915
InChIKeyVVMQSDIMNDTMII-GWZGOYLNSA-N
SmilesO=C(NC2=CC=CC3=C2CNC3=O)CN(CC1)CCN1[C@]([C@@H]4O[C@H](N5C=NC6=C5N=CN=C6N)[C@@H](O)[C@H]4O)=O.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO30.5250
water3.055mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight610.45.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.64mL8.19mL16.38mL
5mM0.33mL1.64mL3.28mL
10mM0.16mL0.82mL1.64mL
50mM0.03mL0.16mL0.33mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet