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主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > Other_enzymes > Tocris/EX 527/2780/10/10毫克
商品详细Tocris/EX 527/2780/10/10毫克
Tocris/EX 527/2780/10/10毫克
Tocris/EX 527/2780/10/10毫克
商品编号: 2780/10
品牌: Tocris Bioscience
市场价: ¥3780.00
美元价: 2268.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:SelectiveSIRT1inhibitor
ChemicalName:6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveinhibitorofSIRT1thatdoesnotinhibithistonedeacetylase(HDAC)orothersirtuindeacetylasefamilymembers(IC50valuesare98,19600,48700,>100000and>100000nMforSIRT1,SIRT2,SIRT3,HDACandNADaserespectively).Enhancesp53acetylationinresponsetoDNAdamagingagents.

CompoundLibraries

EX527isalsoofferedaspartoftheTocriscreenEpigeneticsToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt248.71
FormulaC13H13ClN2O
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber49843-98-3
PubChemID5113032
InChIKeyFUZYTVDVLBBXDL-UHFFFAOYSA-N
SmilesClC1=CC=C(NC3=C2CCCC3C(N)=O)C2=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO18.6575
ethanol12.4450

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight248.71.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.02mL20.1mL40.21mL
5mM0.8mL4.02mL8.04mL
10mM0.4mL2.01mL4.02mL
50mM0.08mL0.4mL0.8mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet