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商品详细Tocris/Eact/4876/50/50 mg

Tocris/Eact/4876/50/50 mg

商品编号： 4876/50

品牌： Tocris Bioscience

市场价： ¥14100.00

美元价： 8460.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:ActivatorofCa²⁺-activatedCl^-channeltransmembraneprotein16A(TMEM16A)

ChemicalName:3,4,5-Trimethoxy-N-(2-methoxyethyl)-N-(4-phenyl-2-thiazolyl)benzamide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

TMEM16A(ANO1)calcium-activatedchloridechannel(CaCC)activator(EC₅₀=3μM).Alsotransientreceptorpotentialvanilloid1(TRPV1)channelactivator(EC₅₀=11.6μM).Ca²⁺-independent.DisplaysnoeffectonCFTRCl^-orENaCNa⁺conductance.Stimulatessubmucosalglandsecretioninhumanbronchi.

CompoundLibraries

EactisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	428.5
Formula	C₂₂H₂₄N₂O₅S
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	461000-66-8
PubChemID	3173542
InChIKey	ZUXNHFFVQWADJL-UHFFFAOYSA-N
Smiles	O=C(C3=CC(OC)=C(OC)C(OC)=C3)N(CCOC)C1=NC(C2=CC=CC=C2)=CS1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	42.85	100
	ethanol	4.29	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight428.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.33mL	11.67mL	23.34mL
5mM	0.47mL	2.33mL	4.67mL
10mM	0.23mL	1.17mL	2.33mL
50mM	0.05mL	0.23mL	0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ReconstitutionCalculator

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ProductDatasheets