Biological Activity
Tachykinin receptor ligand; analog of substance P.
Technical Data
| M. Wt | 706.94 |
| Formula | C34H58N8O6S |
| Sequence |
KFIGLM (Modifications: Met-6 = C-terminal amide) |
| Storage | Desiccate at -20°C |
| CAS Number | 2990-43-4 |
| PubChem ID | 151058 |
| InChI Key | UCWISUCKJRPWFZ-HFYXWKFHSA-N |
| Smiles | [H]N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Preparing Stock Solutions
The following data is based on the product molecular weight 706.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.41 mL | 7.07 mL | 14.15 mL |
| 5 mM | 0.28 mL | 1.41 mL | 2.83 mL |
| 10 mM | 0.14 mL | 0.71 mL | 1.41 mL |
| 50 mM | 0.03 mL | 0.14 mL | 0.28 mL |
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Product Datasheets
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References
References are publications that support the products' biological activity.
Gater et al (1982) Relative activities of substance P-related peptides in the guinea-pig ileum and rat parotid gland, in vitro. Br.J.Pharmacol. 75 341 PMID: 6194840
Henry and Sessle (1985) Effects of glutamate, substance P and eledoisin-related peptide on solitary tract neurones involved in respiration and respiratory reflexes. Neuroscience 14 863 PMID: 2581174
Torrens et al (1985) Pharmacological characterisation of two tachykinin binding sites in the rat cerebral cortex. Neuropeptides 6 59 PMID: 2581167
Keywords: Eledoisin related peptide, supplier, Tachykinin, receptors, ligands, Non-Selective, Neurokinin, Other, Tachykinin, Other, Tachykinin, Tocris Bioscience
