托克里斯/恩他卡彭/4720/50/50毫克-免疫在线蚂蚁淘旗下平台

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商品详细托克里斯/恩他卡彭/4720/50/50毫克

托克里斯/恩他卡彭/4720/50/50毫克

商品编号： 4720/50

品牌： Tocris Bioscience

市场价： ¥4500.00

美元价： 2700.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentCOMTinhibitor;blocksα-synucleinaggregation

ChemicalName:(2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentcatecholO-methyltransferase(COMT)inhibitor(IC₅₀valuesare14.3,20.1and73.3nMforratliversolubleCOMT,totalCOMTandmembrane-boundCOMTrespectively).IncreasesbioavailABIlityoflevodopawhengivenasanadjuncttherapyforParkinson'sdisease.Inhibitsα-synucleinaggregationinaninvitroassay;blocksα-synuclein-inducedcelldeathinPC-12cells.

TechnicalData

M.Wt	305.29
Formula	C₁₄H₁₅N₃O₅
Storage	StoreatRT
Purity	≥99%(HPLC)
CASNumber	130929-57-6
PubChemID	5281081
InChIKey	JRURYQJSLYLRLN-BJMVGYQFSA-N
Smiles	OC1=CC(/C=C(C#N)/C(N(CC)CC)=O)=CC([N+]([O-])=O)=C1O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	30.53	100
	ethanol	3.05	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight305.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.28mL	16.38mL	32.76mL
5mM	0.66mL	3.28mL	6.55mL
10mM	0.33mL	1.64mL	3.28mL
50mM	0.07mL	0.33mL	0.66mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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TechnicalData

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