4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > Other_enzymes > Tocris/FAK Inhibitor 14/3414/10/10 mg
商品详细Tocris/FAK Inhibitor 14/3414/10/10 mg
Tocris/FAK Inhibitor 14/3414/10/10 mg
Tocris/FAK Inhibitor 14/3414/10/10 mg
商品编号: 3414/10
品牌: Tocris Bioscience
市场价: ¥2180.00
美元价: 1308.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:SelectiveFAKinhibitor
AlternativeNames:Y15,NSC677249
ChemicalName:1,2,4,5-Benzenetetraminetetrahydrochloride
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivefocaladhesionkinase(FAK)inhibitorthatdisplaysnosignificantactivityatarangeofotherkinasesincludingEGFR,PDGFRandIGF-RI.PreventsFAKautophosphorylationatY397(IC50=1μM),promotescelldetachmentandinhibitscelladhesioninvitro.Exhibitsantiproliferativeactivityinavarietyofhumantumorcelllinesinvitroandinbreastcancercellsinvivo.

TechnicalData

M.Wt284.01
FormulaC6H10N4.4HCl
StorageDesiccateatRT
CASNumber4506-66-5
PubChemID78260
InChIKeyBZDGCIJWPWHAOF-UHFFFAOYSA-N
SmilesNC1=C(N)C=C(N)C(N)=C1.Cl.Cl.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO21.375
ethanol1.425
water14.250

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight284.01.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.52mL17.61mL35.21mL
5mM0.7mL3.52mL7.04mL
10mM0.35mL1.76mL3.52mL
50mM0.07mL0.35mL0.7mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet