BiologicalActivity
SelectiveSEROtoninreuptakeinhibitor.Bindstothehuman5-HTtransporterwithaKiof0.9nmol/landisbetween150-and900-foldselectiveover5-HT1A,5-HT2A,H1,α1,α2-adrenergic,andmuscarinicreceptors.Antidepressant.Inducesdifferentiationofneuronalprecursors,enhancingneuronalcharacteristics.
LicensingInformation
SoldwiththepermissionofEliLillyandCompany
CompoundLibraries
FluoxetinehydrochlorideisalsoofferedaspartoftheTocriscreenPlusandTocriscreenStemCellToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 345.78 |
| Formula | C17H18F3NO.HCl |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 56296-78-7 |
| PubChemID | 62857 |
| InChIKey | GIYXAJPCNFJEHY-UHFFFAOYSA-N |
| Smiles | Cl.CNCCC(OC1=CC=C(C=C1)C(F)(F)F)C1=CC=CC=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 34.58 | 100 | |
| water | 3.46 | 10 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight345.78.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.89mL | 14.46mL | 28.92mL |
| 5mM | 0.58mL | 2.89mL | 5.78mL |
| 10mM | 0.29mL | 1.45mL | 2.89mL |
| 50mM | 0.06mL | 0.29mL | 0.58mL |
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ProductDatasheets
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