托克里斯/氟伐他汀钠/3309/50/50毫克-免疫在线蚂蚁淘旗下平台

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商品详细托克里斯/氟伐他汀钠/3309/50/50毫克

托克里斯/氟伐他汀钠/3309/50/50毫克

商品编号： 3309/50

品牌： Tocris Bioscience

市场价： ¥2300.00

美元价： 1380.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentHMG-CoAreductaseinhibitor

ChemicalName:(±)-(3R*,5S*,6E)-7-[3-(4-Fluorophenyl)-1-(1-methyethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoicacidsodiumsalt

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Orallyactive,potentandcompetitiveHMG-CoAreductaseinhibitor(IC₅₀=40-100nMathumanlivermicrosomes).Inhibitsvascularsmoothmuscleproliferationinvitro(IC₅₀=70nM)andexhibitsantihypercholesterolemicandantioxidantactivityinvivo.

CompoundLibraries

FluvastatinsodiumisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	433.45
Formula	C₂₄H₂₅FNNaO₄
Storage	Desiccateat-20°C
Purity	≥98%(HPLC)
CASNumber	93957-55-2
PubChemID	76969265
InChIKey	BNZHURJBOKXWJX-ZKBIPVLYSA-L
Smiles	[Na+].[Na+].CC(C)N1C(C=C[C@H](O)C[C@H](O)CC([O-])=O)=C(C2=CC=C(F)C=C2)C2=C1C=CC=C2.CC(C)N1C(C=C[C@@H](O)C[C@@H](O)CC([O-])=O)=C(C2=CC=C(F)C=C2)C2=C1C=CC=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	43.34	100
	ethanol	10.84	25
	water	10.84	25

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight433.45.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.31mL	11.54mL	23.07mL
5mM	0.46mL	2.31mL	4.61mL
10mM	0.23mL	1.15mL	2.31mL
50mM	0.05mL	0.23mL	0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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