Tocris/GI 254023X/3995/1/1 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/GI 254023X/3995/1/1 mg

Tocris/GI 254023X/3995/1/1 mg

商品编号： 3995/1

品牌： Tocris Bioscience

市场价： ¥3300.00

美元价： 1980.00

产地：美国(厂家直采)

公司：

产品分类：蛋白酶类

公司分类： protease

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:SelectiveADAM10metalloproteaseinhibitor

ChemicalName:(2R)-N-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl]propyl]-2-[(1S)-1-(N-hydroxyformamido)ethyl]-5-phenylpentanamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveADAM10metalloproteaseinhibitor;displaysover100-foldhigherpotencyatADAM10comparedtoADAM17.BlocksconstitutivereleaseofIL-6R,CX3CL1andCXCL16incell-basedcleavageexperiments.Inhibitscalciumionophore-inducedbetacellulinsheddinginIMPEcells.PreventsE-cadherincleavageinA549cells.

LicensingInformation

SoldforresearchpurposesunderagreementfromGlaxoSmithKline.

TechnicalData

M.Wt	391.5
Formula	C₂₁H₃₃N₃O₄
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	260264-93-5
PubChemID	9952396
InChIKey	GHVMTHKJUAOZJP-CGTJXYLNSA-N
Smiles	CNC([C@H]([C@@](C)(C)C)NC([C@H](CCCC1=CC=CC=C1)[C@H](C)N(O)C([H])=O)=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	7.83	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight391.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.55mL	12.77mL	25.54mL
5mM	0.51mL	2.55mL	5.11mL
10mM	0.26mL	1.28mL	2.55mL
50mM	0.05mL	0.26mL	0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

LicensingInformation

TechnicalData

SolubilityData

PreparingStockSolutions

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