Tocris/GKA 50/5133/10/10毫克-免疫在线蚂蚁淘旗下平台

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Tocris/GKA 50/5133/10/10毫克

商品编号： 5133/10

品牌： Tocris Bioscience

市场价： ¥5100.00

美元价： 3060.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Glucokinaseactivator

ChemicalName:6-[[3-[(1S)-2-Methoxy-1-methylethoxy]-5-[(1S)-1-methyl-2-phenylethoxy]benzoyl]amino-3-pyridinecarboxylicacid

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentglucokinaseactivator(EC₅₀=33nM).Significantlyreducesplasmaglucoselevelsindiabeticrats;stimulatesinsulinreleasefrommouseisletsofLangerhans.

CompoundLibraries

GKA50isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	464.51
Formula	C₂₆H₂₈N₂O₆
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	851884-87-2
PubChemID	11340230
InChIKey	OCBMECSFDVUYQN-ROUUACIJSA-N
Smiles	O=C(NC3=NC=C(C(O)=O)C=C3)C1=CC(O[C@@H](C)COC)=CC(O[C@@H](C)CC2=CC=CC=C2)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	46.45	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight464.51.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.15mL	10.76mL	21.53mL
5mM	0.43mL	2.15mL	4.31mL
10mM	0.22mL	1.08mL	2.15mL
50mM	0.04mL	0.22mL	0.43mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

MolarityCalculator

ReconstitutionCalculator

DilutionCalculator

ProductDatasheets