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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > Target_Expression > Tocris/GN 44028/5655/10/10毫克
商品详细Tocris/GN 44028/5655/10/10毫克
Tocris/GN 44028/5655/10/10毫克
Tocris/GN 44028/5655/10/10毫克
商品编号: 5655/10
品牌: Tocris Bioscience
市场价: ¥3580.00
美元价: 2148.00
产地: 美国(厂家直采)
公司:
产品分类: 转录表达
公司分类: Target_Expression
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:PotentHIF-1αinhibitor
ChemicalName:N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentHIF-1αinhibitor(IC50=14nM).Inhibitshypoxia-inducedHIF-1αtranscriptionalactivitywithoutsuppressingHIF-1αmRNAexpression,HIF-1αproteinaccumulation,orHIF-1α/HIF-1βheterodimerization.Cytotoxictoarangeofcancercelltypesinvitro.

TechnicalData

M.Wt305.33
FormulaC18N15N3O2
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1421448-26-1
PubChemID71625259
InChIKeyCGZKSZVSWAAUHE-UHFFFAOYSA-N
SmilesC12=CC=CC=C1C3=C(C(NC4=CC(OCCO5)=C5C=C4)=NN3)C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO30.53100
ethanol30.53100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight305.33.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.28mL16.38mL32.75mL
5mM0.66mL3.28mL6.55mL
10mM0.33mL1.64mL3.28mL
50mM0.07mL0.33mL0.66mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet