Tocris/GPP 78 hydrochloride/4835/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/GPP 78 hydrochloride/4835/50/50 mg

Tocris/GPP 78 hydrochloride/4835/50/50 mg

商品编号： 4835/50

品牌： Tocris Bioscience

市场价： ¥18100.00

美元价： 10860.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:NAMPTinhibitor;alsoinducesautophagy

ChemicalName:N-[1,1'-Biphenyl]-2-yl-4-(3-pyridinyl)-1H,1,2,3-triazole-1-octanamidehydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofnicotinamidephosphoribosyltransferase(NAMPT);potentlydepletesNADlevelsandexhibitscytotoxicityinvitro(IC₅₀valuesare3.0and3.8nMrespectively).Alsoshowntoinduceautophagyinneuroblastomacells.

CompoundLibraries

GPP78hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	476.01
Formula	C₂₇H₂₉N₅O.HCl
Storage	Storeat-20°C
Purity	≥98%(HPLC)
PubChemID	90488976
InChIKey	WNZSQRVUGCAYDC-UHFFFAOYSA-N
Smiles	O=C(NC3=C(C4=CC=CC=C4)C=CC=C3)CCCCCCCN1N=NC(C2=CC=CN=C2)=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	47.6	100
	ethanol	23.8	50
	water	47.6	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight476.01.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.1mL	10.5mL	21.01mL
5mM	0.42mL	2.1mL	4.2mL
10mM	0.21mL	1.05mL	2.1mL
50mM	0.04mL	0.21mL	0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets