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InactivecontrolofGSKJ1(CatNo.4593)(IC50>100μMforinhibitionofJMJD3/UTX).Cellpermeableesterderivative,GSKJ5(Cat.No.4689),alsoavailable.
ThiscompoundissuppliedinconjunctionwiththeStructuralGenomicsConsortium.ForfurtherdetailsofGSKJ2,aninactiveisomerofGSKJ1,pleasevisittheGSKJ1probesummaryontheSGCwebsite.
GSKJ2isalsoofferedaspartoftheTocriscreenPlusandTocriscreenEpigeneticsToolbox.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Thefollowingdataisbasedontheproductmolecularweight389.45.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.