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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > kinase > Tocris/GW 2580/5673/10/10 mg
商品详细Tocris/GW 2580/5673/10/10 mg
Tocris/GW 2580/5673/10/10 mg
Tocris/GW 2580/5673/10/10 mg
商品编号: 5673/10
品牌: Tocris Bioscience
市场价: ¥2580.00
美元价: 1548.00
产地: 美国(厂家直采)
公司:
产品分类: 激酶
公司分类: kinase
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:SelectivecFMSkinaseinhibitor;orallybioavailable
ChemicalName:5-[[3-Methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamine
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectivecFMSkinaseinhibitor(IC50=0.06μM).ExhibitsselectivityforcFMSkinaseover186otherkinases.InhibitsCSF-1-inducedgrowthofratmonocytesinvitro.Alsoinhibitsboneresorptioninosteoclastcultures,aswellasconnectivetissueandbonedestructioninaratadjuvantarthritismodel.SuppressesM-NFS-60tumorcellgrowthinmice.Orallybioavailable.

TechnicalData

M.Wt366.41
FormulaC20H22N4O3
StorageStoreat-20°C
Purity≥99%(HPLC)
CASNumber870483-87-7
PubChemID11617559
InChIKeyMYQAUKPBNJWPIE-UHFFFAOYSA-N
SmilesNC1=C(CC2=CC(OC)=C(OCC3=CC=C(OC)C=C3)C=C2)C=NC(N)=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO18.3250

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight366.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.73mL13.65mL27.29mL
5mM0.55mL2.73mL5.46mL
10mM0.27mL1.36mL2.73mL
50mM0.05mL0.27mL0.55mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet