BiologicalActivity
EndogenouscannABInoidandvanilloidreceptoragonist,inwater-solubleemulsion(fordetailsseeTocrisolveTM100,Cat.No.1684).Kivaluesare89and371nMforCB1andCB2receptorsrespectively;EC50valuesare18,31and27nMatGPR55,CB1andCB2respectively;pKi=5.68forrVR1.AlsoblocksTNF-α-inducedNF-kBactivationviadirectinhibitionofIKK.Alsoavailableasthepureoildissolvedinethanol(Anandamine,Cat.No.1339).TocrisolveControl(Cat.No.1684)alsoavailable.
TechnicalData
| M.Wt | 347.54 |
| Formula | C22H37NO2 |
| Storage | Storeat+4°C |
| CASNumber | 94421-68-8 |
| PubChemID | 5281969 |
| InChIKey | LGEQQWMQCRIYKG-DOFZRALJSA-N |
| Smiles | O=C(NCCO)CCCC=C/CC=C/C/C=CC/C=CCCCCC |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight347.54.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.88mL | 14.39mL | 28.77mL |
| 5mM | 0.58mL | 2.88mL | 5.75mL |
| 10mM | 0.29mL | 1.44mL | 2.88mL |
| 50mM | 0.06mL | 0.29mL | 0.58mL |
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