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商品详细Tocris/SR 144528/5039/50/50 mg

Tocris/SR 144528/5039/50/50 mg

商品编号： 5039/50

品牌： Tocris Bioscience

市场价： ¥15300.00

美元价： 9180.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:HighaffinityandselectiveCB₂inverseagoNIST

ChemicalName:5-(4-Chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]-1H-pyrazole-3-carboxamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HighaffinityandselectiveCB₂inverseagonist(K_i=0.6nM).Exhibits>700-foldselectivityforCB₂overCB₁receptors.BlockstheeffectsofCP55,940(Cat.No.0949)onforskolin-sensitiveadenylylcyclaseactivityandMAPKinCHOcellsexpressingCB₂receptors.AlsoblocksCP55,940-inducedB-cellactivation.Orallybioavailable.

TechnicalData

M.Wt	476.05
Formula	C₂₉H₃₄ClN₃O
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	192703-06-3
PubChemID	3081355
InChIKey	SUGVYNSRNKFXQM-XRHWURSXSA-N
Smiles	C[C@]1(C2)[C@H](NC(C3=NN(CC4=CC=C(C)C=C4)C(C5=CC=C(Cl)C(C)=C5)=C3)=O)C(C)(C)[C@@H]2CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	47.6	100
	ethanol	47.6	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight476.05.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.1mL	10.5mL	21.01mL
5mM	0.42mL	2.1mL	4.2mL
10mM	0.21mL	1.05mL	2.1mL
50mM	0.04mL	0.21mL	0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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