![Tocris/[Des-octanoyl]-Ghrelin (rat)/2951/1/1 mg](https://www.ebiomall.cn/images/201712/1512521756115821138.jpg)
Biological Activity
Non-acylated, major circulating isoform of ghrelin that does not bind to the ghrelin receptor (GHS-R1a), nor induce growth hormone release.
Technical Data
| M. Wt | 3188.63 |
| Formula | C139H231N45O41 |
| Sequence | GSSFLSPEHQKAQQRKESKKPPAKLQPR |
| Storage | Desiccate at -20°C |
| CAS Number | 307950-60-3 |
| PubChem ID | 90488789 |
| InChI Key | CMCPTGQGZXKKEH-MGXJLMSJSA-N |
| Smiles | [H]NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 1 mg/ml in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 3188.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 0.31 mL | 1.57 mL | 3.14 mL |
| 5 mM | 0.06 mL | 0.31 mL | 0.63 mL |
| 10 mM | 0.03 mL | 0.16 mL | 0.31 mL |
| 50 mM | 0.01 mL | 0.03 mL | 0.06 mL |
Molarity Calculator
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Product Datasheets
References
References are publications that support the products' biological activity.
Bedendi et al (2003) Cardiac effects of ghrelin and its endogenous derivatives des-octanoyl ghrelin and des-Gln14-ghrelin. Eur.J.Pharmacol. 476 87 PMID: 12969753
Thompson et al (2004) Ghrelin and des-octanoyl ghrelin promote adipogenesis directly in vivo by a mechanism independent of the type 1a growth hormone secretagogue receptor Endocrinology 145 234 PMID: 14551228
Cassoni et al (2004) Expression of ghrelin and biological activity of specific receptors for ghrelin and des-acyl ghrelin in human prostate neoplasms and related cell lines. Eur.J.Endocrinol. 150 173 PMID: 14763915
Keywords: [des-octanoyl]-Ghrelin (rat), supplier, circulating, ghrelin, devoid, activity, GHS-R1a, Receptors, Growth, Hormone, Secretagogue, Receptor, 1a, Ghrelin, Des-acyl, ghrelin, (rat), Ghrelin, Receptors, Ghrelin, Receptors, Tocris Bioscience
