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Tocris Bioscience(优势品牌)
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当前位置: 首页 > 产品中心 > Other_enzymes > Tocris/HA 130/4196/50/50 mg
商品详细Tocris/HA 130/4196/50/50 mg
Tocris/HA 130/4196/50/50 mg
Tocris/HA 130/4196/50/50 mg
商品编号: 4196/50
品牌: Tocris Bioscience
市场价: ¥16500.00
美元价: 9900.00
产地: 美国(厂家直采)
公司:
产品分类: 其它酶
公司分类: Other_enzymes
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:Potentandselectiveautotaxininhibitor
ChemicalName:B-[3-[[4-[[3-[(4-Fluorophenyl)methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]phenyl]-boronicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectiveautotaxininhibitor(IC50=28nM).BindsandinhibitsautotaxinreversIBLy.Displaysnoactivityagainsttheproteasome,recombinantNPP1oralkalinephosphatase.InhibitsATX-mediatedcellmigrationinanA2058melanomacellassay.

CompoundLibraries

HA130isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt463.29
FormulaC24H19BFNO5S
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber1229652-21-4
PubChemID46911532
InChIKeyVTNKMYWFWQTEHE-XKZIYDEJSA-N
SmilesFC1=CC=C(CN3C(/C(SC3=O)=C/C2=CC=C(OCC4=CC(B(O)O)=CC=C4)C=C2)=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO46.33100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight463.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.16mL10.79mL21.58mL
5mM0.43mL2.16mL4.32mL
10mM0.22mL1.08mL2.16mL
50mM0.04mL0.22mL0.43mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet