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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > protease > Tocris/HBX 41108/4285/10/10毫克
商品详细Tocris/HBX 41108/4285/10/10毫克
Tocris/HBX 41108/4285/10/10毫克
Tocris/HBX 41108/4285/10/10毫克
商品编号: 4285/10
品牌: Tocris Bioscience
市场价: ¥4500.00
美元价: 2700.00
产地: 美国(厂家直采)
公司:
产品分类: 蛋白酶类
公司分类: protease
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:SelectiveUSP7inhibitor
ChemicalName:7-Chloro-9-oxo-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofubiquitin-specificprotease(USP)7activity(IC50=424nM).Displaysuncompetitiveinhibition.AlsoinhibitsUSP7-mediatedp53deubiquitination(IC50=0.8μM).StABIlizesp53andinhibitscancercellgrowth;inducesp53-dependentapoptosisinp53wildtypeandnullisogeniccancercelllines.

LicensingInformation

SoldforresearchuseonlyunderpatentlicensefromHybrigenicsS.A.

TechnicalData

M.Wt266.64
FormulaC13H3ClN4O
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber924296-39-9
PubChemID16065773
InChIKeyBIGPXXAUSQLTQR-UHFFFAOYSA-N
SmilesO=C2C1=CC(Cl)=CC=C1C3=C2N=C(C#N)C(C#N)=N3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO26.66100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight266.64.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.75mL18.75mL37.5mL
5mM0.75mL3.75mL7.5mL
10mM0.38mL1.88mL3.75mL
50mM0.08mL0.38mL0.75mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet