Tocris/(±)-HIP-A/2217/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/(±)-HIP-A/2217/10/10 mg

Tocris/(±)-HIP-A/2217/10/10 mg

商品编号： 2217/10

品牌： Tocris Bioscience

市场价： ¥3780.00

美元价： 2268.00

产地：美国(厂家直采)

公司：

产品分类：转运体

公司分类： Transporters

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Potent,non-competitiveEAATinhibitor

ChemicalName:(±)-3-Hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]isoxazole-4-carboxylicacid

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,non-competitiveexcitatoryaminoacidtransporter(EAAT)blocker.Preferentiallyinhibitsglutamate-induced[³H]D-aspartaterelease(IC₅₀=1.6μM)ratherthan[³H]L-glutamateuptake(IC₅₀=18μM).Moderatelyselective;displaysnoaffinityforNMDAandmetabotropicglutamatereceptors,andlowaffinityforAMPAandkainatereceptors(IC₅₀valuesare43and8μMrespectively). .

TechnicalData

M.Wt	172.14
Formula	C₆H₈N₂O₄
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	227619-64-9
PubChemID	90488747
InChIKey	SKTBUVYVLORGED-ACIRMZHZSA-N
Smiles	OC1=NO[C@@]2([H])[C@@]([H])1[C@H]([C@@](O)=O)NC2.OC3=NO[C@]4([H])[C@]([H])3[C@@H](C(O)=O)NC4

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	water	1.72	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight172.14.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	5.81mL	29.05mL	58.09mL
5mM	1.16mL	5.81mL	11.62mL
10mM	0.58mL	2.9mL	5.81mL
50mM	0.12mL	0.58mL	1.16mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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