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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > DNA_polymerase > Tocris/4-HQN/2192/50/50 mg
商品详细Tocris/4-HQN/2192/50/50 mg
Tocris/4-HQN/2192/50/50 mg
Tocris/4-HQN/2192/50/50 mg
商品编号: 2192/50
品牌: Tocris Bioscience
市场价: ¥1900.00
美元价: 1140.00
产地: 美国(厂家直采)
公司:
产品分类: DNA聚合酶
公司分类: DNA_polymerase
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:PARPinhibitor
ChemicalName:4-(1H)-Quinazolinone
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofpoly(ADP-ribose)polymerase(PARP)(IC50=9.5μM);displaysmixedinhibitionwithrespecttoNAD+.Protectiveagainstischemia-reperfusioninducedROSproduction,andsubsequentmitochondrialandcelldamageinratheart.Anti-inflammatoryinLPS-inducedendotoxicmiceinvivo;decreasesNF-κBandAP-1activation.

TechnicalData

M.Wt146.15
FormulaC8H6N2O
StorageDesiccateatRT
Purity≥99%(HPLC)
CASNumber491-36-1
PubChemID63112
InChIKeyQMNUDYFKZYBWQX-UHFFFAOYSA-N
SmilesOC1=C2C=CC=CC2=NC=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO14.62100
water1.4610

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight146.15.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM6.84mL34.21mL68.42mL
5mM1.37mL6.84mL13.68mL
10mM0.68mL3.42mL6.84mL
50mM0.14mL0.68mL1.37mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet