Biological Activity
Selective antagonist at GABAB receptors.
Technical Data
| M. Wt | 265.71 |
| Formula | C9H12ClNO4S |
| Storage | Store at RT |
| CAS Number | 117354-64-0 |
| PubChem ID | 1564 |
| InChI Key | WBSMZVIMANOCNX-UHFFFAOYSA-N |
| Smiles | NCC(O)(CS(O)(=O)=O)C1=CC=C(Cl)C=C1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 5 mM in water and to 100 mM in 1eq. NaOH |
Preparing Stock Solutions
The following data is based on the product molecular weight 265.71. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.76 mL | 18.82 mL | 37.64 mL |
| 5 mM | 0.75 mL | 3.76 mL | 7.53 mL |
| 10 mM | 0.38 mL | 1.88 mL | 3.76 mL |
| 50 mM | 0.08 mL | 0.38 mL | 0.75 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Curtis et al (1988) Baclofen antagonism by 2-hydroxysaclofen in the cat spinal cord. Neurosci.Lett. 92 97 PMID: 2847093
Kerr et al (1988) 2-Hydroxysaclofen: an improved antagonist at central and peripheral GABAB receptors. Neurosci.Lett. 92 92 PMID: 2847092
Keywords: 2-Hydroxysaclofen, supplier, Selective, GABAB, antagonists, Receptors, GABAB, Receptors, GABAB, Receptors, Tocris Bioscience
