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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > Signal_pathway > Tocris/IC 87201/6226/50/50 mg
商品详细Tocris/IC 87201/6226/50/50 mg
Tocris/IC 87201/6226/50/50 mg
Tocris/IC 87201/6226/50/50 mg
商品编号: 6226/50
品牌: Tocris Bioscience
市场价: ¥15900.00
美元价: 9540.00
产地: 美国(厂家直采)
公司:
产品分类: 信号通路
公司分类: Signal_pathway
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:nNOS-PSD95protein-proteininteractioninhibitor;alsoantinociceptiveandantidepressant
ChemicalName:2-[(1H-Benzotriazol-6-ylamino)methyl]-4,6-dichlorophenol
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitsbindingoftheNMDAreceptorpostsynapticdensityprotein95kDa(PSD95)tonNOS(EC50=23.94μM),whilenotaffectingthePSD95-ErbB4interaction.Inhibitsglutamate-inducedcelldeathinculturedcorticalneurons.Exhibitsantinociceptiveeffectsininflammatorypainmodelsinvivo.Alsoexhibitsantidepressant-likeactivitiyinanimalmodels.

TechnicalData

M.Wt309.15
FormulaC13H10Cl2N4O
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber866927-10-8
PubChemID11771269
InChIKeyQEHVTUCLCBXQIC-UHFFFAOYSA-N
SmilesOC1=C(C=C(C=C1Cl)Cl)CNC2=CC=C3N=NNC3=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto100mMinDMSOandto100mMinethanol

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight309.15.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.23mL16.17mL32.35mL
5mM0.65mL3.23mL6.47mL
10mM0.32mL1.62mL3.23mL
50mM0.06mL0.32mL0.65mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet