Tocris/ICG 001/4505/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/ICG 001/4505/10/10 mg

Tocris/ICG 001/4505/10/10 mg

商品编号： 4505/10

品牌： Tocris Bioscience

市场价： ¥4500.00

美元价： 2700.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:InhibitsTCF/β-catenin-mediatedtranscription

ChemicalName:(6S,9aS)-Hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofTCF/β-catenin-mediatedtranscription.Selectivelyinhibitsβ-catenin/CBPinteraction;displaysnoeffectonβ-catenin/p300interaction.Exhibitsgrowthinhibitoryeffectsincoloncarcinomacelllines(SW480andHCT-116cells);alsodisplaysefficacyinMinmouseandnudemouseSW620xenograftmodels.

TechnicalData

M.Wt	548.63
Formula	C₃₃H₃₂N₄O₄
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	847591-62-2
PubChemID	11238147
InChIKey	HQWTUOLCGKIECB-XZWHSSHBSA-N
Smiles	O=C1CCN(C(NCC5=CC=CC=C5)=O)[C@]2([H])N1[C@@H](CC6=CC=C(O)C=C6)C(N(CC3=C(C=CC=C4)C4=CC=C3)C2)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	54.86	100
	ethanol	27.43	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight548.63.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.82mL	9.11mL	18.23mL
5mM	0.36mL	1.82mL	3.65mL
10mM	0.18mL	0.91mL	1.82mL
50mM	0.04mL	0.18mL	0.36mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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