Biological Activity
Selective δ opioid antagonist.
Licensing Information
Sold with the permission of AstraZeneca UK Ltd.
Technical Data
| M. Wt | 638.83 |
| Formula | C34H46N4O6S |
| Sequence |
YGFL (Modifications: Tyr-1 = N,N-diallyl-Tyr, Gly-2 - Phe-3 peptide bond replaced with Psi-(CH2S)) |
| Storage | Desiccate at -20°C |
| CAS Number | 83420-94-4 |
| PubChem ID | 3035055 |
| InChI Key | CZRZYRKTYLLLRL-DTXPUJKBSA-N |
| Smiles | CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)SCCNC(=O)CNC(=O)[C@H](CC1=CC=C(O)C=C1)N(CC=C)CC=C)C(O)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 1 mg/ml in methanol |
Preparing Stock Solutions
The following data is based on the product molecular weight 638.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.57 mL | 7.83 mL | 15.65 mL |
| 5 mM | 0.31 mL | 1.57 mL | 3.13 mL |
| 10 mM | 0.16 mL | 0.78 mL | 1.57 mL |
| 50 mM | 0.03 mL | 0.16 mL | 0.31 mL |
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Product Datasheets
on-line. Please contact Customer Service
References
References are publications that support the products' biological activity.
Shaw et al (1982) Selective antagonists at the opiate delta-receptor. Life Sci. 31 1259 PMID: 6128652
Rees and Hunter (1990) Opioid Receptors. Comprehensive Medicinal Chemistry. Ed. Hansch. 3 805 PMID:
Keywords: ICI 154,129, supplier, δ-opioid, delta-opioid, selective, peptide, antagonists, DOP, Receptors, OP1, ICI154129, AstraZeneca, Delta, Opioid, Receptors, Delta, Opioid, Receptors, Tocris Bioscience
