Biological Activity
Potent thromboxane receptor antagonist.
Licensing Information
Sold with the permission of AstraZeneca UK Ltd.
Technical Data
| M. Wt | 374.36 |
| Formula | C18H21F3O5 |
| Storage | Desiccate at -20°C |
| CAS Number | 106393-80-0 |
| PubChem ID | 5311390 |
| InChI Key | ZWAVGFSZMACJHA-PMNBYGLBSA-N |
| Smiles | OC(=O)CCCC=C/C[C@@H]1CO[C@@H](O[C@@H]1C1=C(O)C=CC=C1)C(F)(F)F |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble in DMSO |
Preparing Stock Solutions
The following data is based on the product molecular weight 374.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.67 mL | 13.36 mL | 26.71 mL |
| 5 mM | 0.53 mL | 2.67 mL | 5.34 mL |
| 10 mM | 0.27 mL | 1.34 mL | 2.67 mL |
| 50 mM | 0.05 mL | 0.27 mL | 0.53 mL |
Molarity Calculator
Reconstitution Calculator
Dilution Calculator
Product Datasheets
on-line. Please contact Customer Service
References
References are publications that support the products' biological activity.
Birch et al (1988) Studies in the guinea-pig with ICI 185,282: a thromboxane A2 receptor antagonist. J.Pharm.Pharmacol. 40 706 PMID: 2907537
Keywords: ICI 185,282, supplier, Potent, thromboxane, A2, TXA2, receptors, antagonists, TP, Prostanoid, prostaglandins, prostacyclins, eicosanoids, ICI185282, AstraZeneca, Prostanoid, Receptors, Prostanoid, Receptors, Tocris Bioscience
