Tocris/IWP 2/3533/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/IWP 2/3533/10/10 mg

Tocris/IWP 2/3533/10/10 mg

商品编号： 3533/10

品牌： Tocris Bioscience

市场价： ¥3380.00

美元价： 2028.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PORCNinhibitor;inhibitsWntprocessingandsecretion

ChemicalName:N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitorofWntprocessingandsecretion.InactivatesPORCN,amembrane-boundO-acyltransferase(MBOAT),andselectivelyinhibitspalmitoylationofWnt.BlocksWnt-dependentphosphorylationofLrp6receptorandDvl2,andβ-cateninaccumulation.Suppressesself-renewalinR1embryonicstemcells.

TechnicalData

M.Wt	466.6
Formula	C₂₂H₁₈N₄O₂S₃
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	686770-61-6
PubChemID	2155128
InChIKey	WRKPZSMRWPJJDH-UHFFFAOYSA-N
Smiles	O=C1C3=C(CCS3)N=C(SCC(NC4=NC(C=CC(C)=C5)=C5S4)=O)N1C2=CC=CC=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	2.33	5mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight466.6.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.14mL	10.72mL	21.43mL
5mM	0.43mL	2.14mL	4.29mL
10mM	0.21mL	1.07mL	2.14mL
50mM	0.04mL	0.21mL	0.43mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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TechnicalData

SolubilityData

PreparingStockSolutions

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