Biological Activity
NMDA and metabotropic glutamate receptor agonist.
Technical Data
| M. Wt | 158.11 |
| Formula | C5H6N2O4 |
| Storage | Desiccate at -20°C |
| Purity | ≥98% (HPLC) |
| CAS Number | 2552-55-8 |
| PubChem ID | 1233 |
| InChI Key | IRJCBFDCFXCWGO-UHFFFAOYSA-N |
| Smiles | NC(C(O)=O)C1=CC(O)=NO1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| 1.1eq. NaOH | 15.81 | 100 | |
| water | 1.58 | 10 |
Preparing Stock Solutions
The following data is based on the product molecular weight 158.11. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 6.32 mL | 31.62 mL | 63.25 mL |
| 5 mM | 1.26 mL | 6.32 mL | 12.65 mL |
| 10 mM | 0.63 mL | 3.16 mL | 6.32 mL |
| 50 mM | 0.13 mL | 0.63 mL | 1.26 mL |
Molarity Calculator
Reconstitution Calculator
Dilution Calculator
Product Datasheets
References
References are publications that support the products' biological activity.
Johnston et al (1968) Central actions of ibotenic acid and muscimol. Biochem.Pharmacol. 17 2488 PMID: 5752907
Nakanishi (1992) Molecular diversity of glutamate receptors and implications for brain functions. Science 258 597 PMID: 1329206
Pin and Duvoisin (1995) The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34 1 PMID: 7623957
Watkins and Evans (1981) Excitatory amino acid transmitters. Annu.Rev.Pharmacol.Toxicol. 21 165 PMID: 6112965
Keywords: Ibotenic acid, supplier, Non-Selective, NMDA, agonists, mGlur, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, Metabotropic, NMDA, Receptors, Non-selective, mGlu, NMDA, Receptors, Tocris Bioscience
