BiologicalActivity
ClassIIIantiarrhythmic.BlockstherapidcomponentofdelayedrectifierK+current(IKr);alsoblockshERGchannelsandL-typeCa2+channels.ShowntoactivateaslowinwardNa+currentinguineapigventricularcells.Usedtoterminateatrialfibrillationandatrialflutter;canprolongQT.
CompoundLibraries
IbutilidehemifumarateisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 442.61 |
| Formula | C20H36N2O3S.½C4H4O4 |
| Storage | StoreatRT |
| Purity | ≥98%(HPLC) |
| CASNumber | 122647-32-9 |
| PubChemID | 5281065 |
| InChIKey | PCIOHQNIRPWFMV-WXXKFALUSA-N |
| Smiles | CCCCCCCN(CC)CCCC(O)C1=CC=C(NS(C)(=O)=O)C=C1.O=C(/C=C/C(O)=O)O.CCCCCCCN(CC)CCCC(O)C2=CC=C(NS(C)(=O)=O)C=C2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 44.26 | 100 | |
| ethanol | 44.26 | 100 | |
| water | 44.26 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight442.61.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.26mL | 11.3mL | 22.59mL |
| 5mM | 0.45mL | 2.26mL | 4.52mL |
| 10mM | 0.23mL | 1.13mL | 2.26mL |
| 50mM | 0.05mL | 0.23mL | 0.45mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
本网站将在规定时间内给予删除等相关处理。
