Tocris/5-Iodo-A-85380 dihydrochloride/1518/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/5-Iodo-A-85380 dihydrochloride/1518/10/10 mg

Tocris/5-Iodo-A-85380 dihydrochloride/1518/10/10 mg

商品编号： 1518/10

品牌： Tocris Bioscience

市场价： ¥5580.00

美元价： 3348.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Highaffinityα4β2andα6β2subtype-selectiveagoNIST

ChemicalName:3-[(2S)-2-Azetidinylmethoxy]-5-iodopyridinedihydrochloride

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Ahighlypotentandsubtype-selectiveagonistfortheα4β2andα6β2nicotinicacetylcholinereceptors.Activatesα-CTx-MII-sensitiveand-insensitivecomponentsof[³H]dopaminereleasefromratstriatalsynaptosomes,correspondingtoα6β2andα4β2(EC₅₀valuesare12.7and~35nMrespectively).~5000-,25000-and140000-foldselectiveoverα3β4,α7andmusclenAChRreceptorsrespectively.Precursor(Cat.No.1527)alsoavailable.

TechnicalData

M.Wt	363.03
Formula	C₉H₁₁IN₂O.2HCl
Storage	Desiccateat+4°C
Purity	≥99%(HPLC)
CASNumber	1217837-17-6
PubChemID	54758463
InChIKey	ZJVVFYWEBSHGBV-JZGIKJSDSA-N
Smiles	IC1=CN=CC(OC[C@@H]2CCN2)=C1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	36.3	100
	water	36.3	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight363.03.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.75mL	13.77mL	27.55mL
5mM	0.55mL	2.75mL	5.51mL
10mM	0.28mL	1.38mL	2.75mL
50mM	0.06mL	0.28mL	0.55mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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