Tocris/JJKK 048/5206/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/JJKK 048/5206/10/10 mg

Tocris/JJKK 048/5206/10/10 mg

商品编号： 5206/10

品牌： Tocris Bioscience

市场价： ¥3900.00

美元价： 2340.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:PotentandselectiveMAGLinhibitor

ChemicalName:4-[Bis(1,3-benzodioxol-5-yl)methyl]-1-piperidinyl]-1H-1,2,4-triazol-1-yl-methanone

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectivemonoacylglycerollipase(MAGL)inhibitor(IC₅₀=0.4nM).Exhibits>13,000and~630-foldselectivityforMAGLoverFAAHandABHD6,respectively.Increasesbrainlevelsof2-arachidonoylglycerol(2-AG)levelsinmiceinvivo.Promotesanalgesiainpainmodels.

TechnicalData

M.Wt	434.44
Formula	C₂₃H₂₂N₄O₅
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	1515855-97-6
PubChemID	76313567
InChIKey	CLSNATLUIXZPMV-UHFFFAOYSA-N
Smiles	O=C(N6C=NC=N6)N(CC5)CCC5C(C2=CC=C(OCO3)C3=C2)C1=CC(OCO4)=C4C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	43.44	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight434.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.3mL	11.51mL	23.02mL
5mM	0.46mL	2.3mL	4.6mL
10mM	0.23mL	1.15mL	2.3mL
50mM	0.05mL	0.23mL	0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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