Tocris/JNJ 17203212/3361/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/JNJ 17203212/3361/10/10 mg

Tocris/JNJ 17203212/3361/10/10 mg

商品编号： 3361/10

品牌： Tocris Bioscience

市场价： ¥3380.00

美元价： 2028.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:ReversIBLe,competitiveandpotentTRPV1antagoNIST

ChemicalName:4-[3-(Trifluoromethyl)-2-pyridinyl]-N-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazinecarboxamide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Reversible,competitiveandpotentTRPV1antagonist(pK_ivaluesare6.5,7.1and7.3atrat,guineapigandhumanTRPV1respectively).Inhibitscapsaicin-andH⁺-inducedchannelactivation(pIC₅₀valuesare6.32and7.23respectively)andexhibitsantitussiveandanalgesicactivityinvivo.

CompoundLibraries

JNJ17203212isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	419.32
Formula	C₁₇H₁₅F₆N₅O
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	821768-06-3
PubChemID	11339118
InChIKey	JFRYYGVYCWYIDQ-UHFFFAOYSA-N
Smiles	O=C(NC3=NC=C(C(F)(F)F)C=C3)N(CC2)CCN2C1=C(C(F)(F)F)C=CC=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	41.93	100
	ethanol	41.93	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight419.32.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.38mL	11.92mL	23.85mL
5mM	0.48mL	2.38mL	4.77mL
10mM	0.24mL	1.19mL	2.38mL
50mM	0.05mL	0.24mL	0.48mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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ProductDatasheets