Tocris/JP 1302 dihydrochloride/2666/10/10 mg-免疫在线蚂蚁淘旗下平台

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Tocris/JP 1302 dihydrochloride/2666/10/10 mg

商品编号： 2666/10

品牌： Tocris Bioscience

市场价： ¥3980.00

美元价： 2388.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Potentandselectiveα_2CantagoNIST

ChemicalName:N-[4-(4-Methyl-1-piperazinyl)phenyl]-9-acridinaminedihydrochloride

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

α_2C-adrenoceptorantagonistthatdisplays~50-foldselectivityoverotherα₂-adrenoceptorsubtypes(K_ivaluesare28,1470,1700and3150nMforhumanα_2C,α_2B,α_2Dandα_2Asubtypesrespectively).Potentlyantagonizesadrenalin-stimulated³⁵GTPγSbindinginvitro(K_B=16nM)andproducesantidepressantandantipsychotic-likeeffectsinvivo.

TechnicalData

M.Wt	441.4
Formula	C₂₄H₂₄N₄.2HCl
Storage	Desiccateat-20°C
Purity	≥99%(HPLC)
CASNumber	1259314-65-2
PubChemID	49855035
InChIKey	VVZOADYFJAJZGL-UHFFFAOYSA-N
Smiles	CN(CC5)CCN5C(C=C4)=CC=C4NC2=C3C(C=CC=C3)=NC1=CC=CC=C12.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	2.2	5
	water	44.14	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight441.4.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.27mL	11.33mL	22.66mL
5mM	0.45mL	2.27mL	4.53mL
10mM	0.23mL	1.13mL	2.27mL
50mM	0.05mL	0.23mL	0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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