Tocris/JTE 013/2392/10/10毫克-免疫在线蚂蚁淘旗下平台

当前位置：首页 > 产品中心 > Receptors > Tocris/JTE 013/2392/10/10毫克

商品详细Tocris/JTE 013/2392/10/10毫克

Tocris/JTE 013/2392/10/10毫克

商品编号： 2392/10

品牌： Tocris Bioscience

市场价： ¥4100.00

美元价： 2460.00

产地：美国(厂家直采)

公司：

产品分类：受体

公司分类： Receptors

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

Description:S1P₂receptorantagoNIST

ChemicalName:1-[1,3-Dimethyl-4-(2-methylethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]-4-(3,5-dichloro-4-pyridinyl)-semicarbazide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Sphingosine-1-phosphate(S1P)receptorantagonist,highlyselectiveforS1P₂(EDG-5).InhibitsS1PbindingtohumanS1P₂receptorswithanIC₅₀valueof17.6nM.Atconcentrationsupto10μM,displays4.2%inhibitionofS1P₃anddoesnotantagonizeS1P₁.EnhancesS1P-inducedangiogenesisinvivo.

CompoundLibraries

JTE013isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	408.29
Formula	C₁₇H₁₉N₇OCl₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	547756-93-4
PubChemID	10223146
InChIKey	RNSLRQNDXRSASX-UHFFFAOYSA-N
Smiles	CC(C)C1=C2C(C)=NN(C)C2=NC(NNC(=O)NC2=CC(Cl)=NC(Cl)=C2)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	40.83	100
	ethanol	40.83	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight408.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.45mL	12.25mL	24.49mL
5mM	0.49mL	2.45mL	4.9mL
10mM	0.24mL	1.22mL	2.45mL
50mM	0.05mL	0.24mL	0.49mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

Selectanotherlanguage:

BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

MolarityCalculator

ReconstitutionCalculator

DilutionCalculator

ProductDatasheets