Tocris/KC 12291盐酸盐/3251/50/50 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/KC 12291盐酸盐/3251/50/50 mg

Tocris/KC 12291盐酸盐/3251/50/50 mg

商品编号： 3251/50

品牌： Tocris Bioscience

市场价： ¥15300.00

美元价： 9180.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:OrallyactiveatypicalNa⁺channelblocker;cardioprotective

ChemicalName:3,4-Dimethoxy-N-methyl-N-[3-[(5-phenyl-1,2,4-thiADIazol-3-yl)oxy]propyl]benzeneethanaminehydrochloride

Purity:≥97%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Orallyactiveatypicalvoltage-gatedsodiumchannelblocker.Inhibitssustainedsodiumcurrents(I_NaL)andpreventsdiastoliccontractureinisolatedatriainvitro(IC₅₀valuesare9.6and0.55-0.79μMrespectively).Displaysanti-ischemic,bradycardicandcardioprotectiveactivityinvivo.

TechnicalData

M.Wt	449.99
Formula	C₂₂H₂₇N₃O₃S.HCl
Storage	Desiccateat+4°C
Purity	≥97%(HPLC)
CASNumber	181936-98-1
PubChemID	22902387
InChIKey	KIJPRQYBNQKUAU-UHFFFAOYSA-N
Smiles	CN(CCCOC2=NSC(C3=CC=CC=C3)=N2)CCC1=CC=C(OC)C(OC)=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	22.5	50
	ethanol	4.5	10
	water	11.25	25

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight449.99.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.22mL	11.11mL	22.22mL
5mM	0.44mL	2.22mL	4.44mL
10mM	0.22mL	1.11mL	2.22mL
50mM	0.04mL	0.22mL	0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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TechnicalData

SolubilityData

PreparingStockSolutions

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