Tocris/KML 29/4872/50/50毫克-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/KML 29/4872/50/50毫克

Tocris/KML 29/4872/50/50毫克

商品编号： 4872/50

品牌： Tocris Bioscience

市场价： ¥13300.00

美元价： 7980.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:HighlypotentandselectiveMAGLinhibitor

ChemicalName:4-[Bis(1,3-benzodioxol-5-yl)hydroxymethyl]-1-piperidinecarboxylicacid2,2,2-trifluoro-1-(trifluoromethyl)ethylester

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Highlyselectiveandpotentmonoacylglycerollipase(MAGL)inhibitor.Exhibitspotentinhibitionofhuman,mouseandratMAGL(IC₅₀valuesare5.9,15and43nM,respectively).ExhibitsnodetectableinhibitionofFAAH(IC₅₀>50000nM).Potentlyandselectivelyblockshydrolysisof2-arachidonoylglycerol(2-AG)inmice(IC₅₀=2.5nMand>50μMfor2-AGandAEArespectively).

LicensingInformation

SoldunderlicensefromTheScrippsResearchInstitute

TechnicalData

M.Wt	549.42
Formula	C₂₄H₂₁F₆NO₇
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	1380424-42-9
PubChemID	71656212
InChIKey	SXHQLPHDBLTFPM-UHFFFAOYSA-N
Smiles	O=C(OC(C(F)(F)F)C(F)(F)F)N(CC5)CCC5C(C2=CC=C(OCO3)C3=C2)(O)C1=CC(OCO4)=C4C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	54.94	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight549.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.82mL	9.1mL	18.2mL
5mM	0.36mL	1.82mL	3.64mL
10mM	0.18mL	0.91mL	1.82mL
50mM	0.04mL	0.18mL	0.36mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

LicensingInformation

TechnicalData

SolubilityData

PreparingStockSolutions

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