Biological Activity
Selective agonist at kainate receptors. Potent excitant and neurotoxin. Also available as part of the Kainate Receptor Tocriset™.
Technical Data
| M. Wt | 213.23 |
| Formula | C10H15NO4 |
| Storage | Store at RT |
| Purity | ≥98% (HPLC) |
| CAS Number | 487-79-6 |
| PubChem ID | 10255 |
| InChI Key | VLSMHEGGTFMBBZ-OOZYFLPDSA-N |
| Smiles | C=[C@@](C)[C@@H]1[C@H](CC(O)=O)[C@@H]([C@](O)=O)NC1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| 1eq. NaOH | 21.32 | 100 | |
| water | 5.33 | 25mM with gentle warming |
Preparing Stock Solutions
The following data is based on the product molecular weight 213.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 4.69 mL | 23.45 mL | 46.9 mL |
| 5 mM | 0.94 mL | 4.69 mL | 9.38 mL |
| 10 mM | 0.47 mL | 2.34 mL | 4.69 mL |
| 50 mM | 0.09 mL | 0.47 mL | 0.94 mL |
Molarity Calculator
Reconstitution Calculator
Dilution Calculator
Product Datasheets
References
References are publications that support the products' biological activity.
Watkins and Evans (1981) Excitatory amino acid transmitters. Annu.Rev.Pharmacol.Toxicol. 21 165 PMID: 6112965
Watkins (1978) Excitatory amino acids. Kainic acid as a Tool in Neurobiology. Edited by E 37 PMID:
Keywords: Kainic acid, supplier, Potent, excitant, neurotoxin, Glutamate, Kainate, Receptors, iGluR, Ionotropic, Kainate, Receptors, Kainate, Receptors, Tocris Bioscience
