Biological Activity
Endogenous ligand for the rodent kisspeptin receptor (KISS1, GPR54). Rodent analog of the C-terminal KiSS-1 peptide, KiSS-1112-121 (Kisspeptin 10, Cat. No. 2570).
Technical Data
| M. Wt | 1318.45 |
| Formula | C63H83N17O15 |
| Sequence | YNWNSFGLRY-NH2 |
| Storage | Store at -20°C |
| CAS Number | 478507-53-8 |
| PubChem ID | 90488921 |
| InChI Key | HVPGTDOCSYBNFC-INXYWQKQSA-N |
| Smiles | [H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(N)=O |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
| Solubility | Soluble to 2 mg/ml in water |
Preparing Stock Solutions
The following data is based on the product molecular weight 1318.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 0.76 mL | 3.79 mL | 7.58 mL |
| 5 mM | 0.15 mL | 0.76 mL | 1.52 mL |
| 10 mM | 0.08 mL | 0.38 mL | 0.76 mL |
| 50 mM | 0.02 mL | 0.08 mL | 0.15 mL |
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Product Datasheets
References
References are publications that support the products' biological activity.
Stafford et al (2002) Identification and characterization of mouse metastasis-suppressor KiSS1 and its G-protein-coupled receptor. Cancer Res. 62 5399 PMID: 12359743
Navarro et al (2004) Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide. Endocrinology 145 4565 PMID: 15242985
Keywords: Kisspeptin 10 (rat), supplier, Endogenous, ligands, KISS1, receptors, hOT7T175/AXOR12/GPR54, Metastin, KISS-derived, Peptide, Kisspeptin10, Kisspeptin, Receptor, Kisspeptin, Receptor, Tocris Bioscience
