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Tocris/L-651,582/3086/50/50 mg

商品编号： 3086/50

品牌： Tocris Bioscience

市场价： ¥16500.00

美元价： 9900.00

产地：美国(厂家直采)

公司：

产品分类：信号通路

公司分类： Signal_pathway

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Ca²⁺channelblocker

AlternativeNames:Carboxyamidotriazole

ChemicalName:5-Amino-1-[[3,5-dichloro-4-(4-chlorobenzoyl)phenyl]methyl]-1H-1,2,3-triazole-4-carboxamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

OrallyactiveCa²⁺channelblocker;inhibitsK⁺-andcarbachol-stimulatedCa²⁺influx(IC₅₀valuesare500and935nMrespectively).Exhibitsantiproliferative,antiangiogenicandantimetastaticactivityinvivoanddisplaysselectivitytowardsnumerousmismatchrepair-deficienttumorcelllinesinvitro.

TechnicalData

M.Wt	424.67
Formula	C₁₇H₁₂Cl₃N₅O₂
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	99519-84-3
PubChemID	108144
InChIKey	WNRZHQBJSXRYJK-UHFFFAOYSA-N
Smiles	ClC1=CC=C(C(C2=C(Cl)C=C(CN3N=NC(C(N)=O)=C3N)C=C2Cl)=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	42.47	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight424.67.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.35mL	11.77mL	23.55mL
5mM	0.47mL	2.35mL	4.71mL
10mM	0.24mL	1.18mL	2.35mL
50mM	0.05mL	0.24mL	0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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