Tocris/LCB 03-0110 dihydrochloride/5592/10/10 mg-免疫在线蚂蚁淘旗下平台

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商品详细Tocris/LCB 03-0110 dihydrochloride/5592/10/10 mg

Tocris/LCB 03-0110 dihydrochloride/5592/10/10 mg

商品编号： 5592/10

品牌： Tocris Bioscience

市场价： ¥3980.00

美元价： 2388.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Potentc-SRCkinaseinhibitor;alsoinhibitsDDR2,BTKandSyk

ChemicalName:3-[[2-[3-(4-Morpholinylmethyl)phenyl]thieno[3,2-b]pyridin-7-yl]amino]phenoldihydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentc-Srckinaseinhibitor(IC₅₀=1.3nM).Alsopotentinhibitorofdiscoidindomainreceptor2(DDR2)familytyrosinekinases,BTKandSyk.SuppressesLPS-inducedactivationofmacrophagesandTGF-β1-inducedactivationoffibroblastsinvitro.Alsoinhibitsactivationofmacrophagesandfibroblastsandsuppressesscarformationinawoundhealingmodel.

TechnicalData

M.Wt	490.45
Formula	C₂₄H₂₃N₃O₂S.2HCl
Storage	DesiccateatRT
Purity	≥98%(HPLC)
PubChemID	121513872
InChIKey	OEWGAUGZPPUIPF-UHFFFAOYSA-N
Smiles	OC1=CC=CC(NC2=CC=NC3=C2SC(C4=CC=CC(CN5CCOCC5)=C4)=C3)=C1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	49.05	100
	water	49.05	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight490.45.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.04mL	10.19mL	20.39mL
5mM	0.41mL	2.04mL	4.08mL
10mM	0.2mL	1.02mL	2.04mL
50mM	0.04mL	0.2mL	0.41mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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TechnicalData

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PreparingStockSolutions

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