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Tocris Bioscience(优势品牌)
主营:主营:分子类,蛋白类,抗体类,生化类试剂
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当前位置: 首页 > 产品中心 > Other_reagents > Tocris/AC 4/5464/50/50毫克
商品详细Tocris/AC 4/5464/50/50毫克
Tocris/AC 4/5464/50/50毫克
Tocris/AC 4/5464/50/50毫克
商品编号: 5464/50
品牌: Tocris Bioscience
市场价: ¥20100.00
美元价: 12060.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Description:PhotoswitchableTRPV1channelblocker
ChemicalName:1,3,4,5-Tetrahydro-7,8-dihydro-N-[2-[4-[2-[4-(trifluoromethyl)phenyl]diazenyl]phenyl]ethyl]-2H-2-benzazepine-2-carbothioamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PhotoswitchableTRPV1channelblocker(IC50=3.1μM).ActsasanantagoNISTintransconformationduringvoltagegatedactivation.Alsoactsasanantagonistinthecisformationduringcapsaicin-inducedTRPV1currents.Switchesconformationfromcistotransat440nmandtranstocisat360nm.Allowsphotoswitchableantagonistandanagonisttobeappliedatthesametime.

TechnicalData

M.Wt514.56
FormulaC26H25F3N4O2S
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber1459809-09-6
PubChemID121513863
InChIKeyCOPZFJSJZPCWFD-UHFFFAOYSA-N
SmilesS=C(NCCC3=CC=C(/N=N/C4=CC=C(C(F)(F)F)C=C4)C=C3)N(CCC2)CC1=C2C=C(O)C(O)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO51.46100
water10.2920mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight514.56.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.94mL9.72mL19.43mL
5mM0.39mL1.94mL3.89mL
10mM0.19mL0.97mL1.94mL
50mM0.04mL0.19mL0.39mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet