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商品详细Tocris/LFM-A13/1300/50/50 mg

Tocris/LFM-A13/1300/50/50 mg

商品编号： 1300/50

品牌： Tocris Bioscience

市场价： ¥14180.00

美元价： 8508.00

产地：美国(厂家直采)

公司：

产品分类：其它酶

公司分类： Other_enzymes

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

Description:Potent,selectiveBTKinhibitor

ChemicalName:2-Cyano-N-(2,5-dibromophenyl)-3-hydroxy-2-butenamide

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveinhibitorofBruton'styrosinekinase(BTK).InhibitsrecombinantBTKwithanIC₅₀valueof2.5μMandhasnoactivityonotherproteinkinases(includingJAK1,JAK3,HCK,EGFRkinaseandinsulinreceptorkinase)atconcentrationsofupto278μM.

TechnicalData

M.Wt	360
Formula	C₁₁H₈Br₂N₂O₂
Storage	StoreatRT
Purity	≥98%(HPLC)
CASNumber	62004-35-7
PubChemID	54676905
InChIKey	UVSVTDVJQAJIFG-VURMDHGXSA-N
Smiles	CC(O)=C(/C#N)C(=O)NC1=C(Br)C=CC(Br)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	36	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight360.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.78mL	13.89mL	27.78mL
5mM	0.56mL	2.78mL	5.56mL
10mM	0.28mL	1.39mL	2.78mL
50mM	0.06mL	0.28mL	0.56mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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